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Constituents and functions of the rat DMN [Neuroscience]

PNAS Early Edition Articles - Wed, 07/20/2016 - 12:46
The default mode network (DMN) has been suggested to support a variety of self-referential functions in humans and has been fractionated into subsystems based on distinct responses to cognitive tasks and functional connectivity architecture. Such subsystems are thought to reflect functional hierarchy and segregation within the network. Because preclinical models...

Cysteine oxidation disrupts energy transfer in FMO [Commentaries]

PNAS Early Edition Articles - Wed, 07/20/2016 - 12:46
Unlike higher plants, which are often awash in sunlight, green sulfur bacteria survive in some of the darkest and most inhospitable environments for photosynthetic organisms. From the bottom of the Black Sea to the underside of thick microbial mats growing atop hot springs, these anaerobic archaea subsist on the rare...

Establishment of epigenetic states in Drosophila [Developmental Biology]

PNAS Early Edition Articles - Wed, 07/20/2016 - 12:46
Epigenetic patterns of histone modifications contribute to the maintenance of tissue-specific gene expression. Here, we show that such modifications also accompany the specification of cell identities by the NF-κB transcription factor Dorsal in the precellular Drosophila embryo. We provide evidence that the maternal pioneer factor, Zelda, is responsible for establishing...

Forces behind plant cell division [Commentaries]

PNAS Early Edition Articles - Wed, 07/20/2016 - 12:46
The cell theory developed in the early 19th century teaches us that only cells beget cells (1). As a consequence, the evolution of life on Earth is but a long sequence of cell divisions; wherever this sequence is broken, life ends. Cell division is not only how organisms perpetuate themselves,...

IRS-1 and proinflammatory phenotype in lung ADCA [Medical Sciences]

PNAS Early Edition Articles - Wed, 07/20/2016 - 12:46
Insulin receptor substrate-1 (IRS-1) is a signaling adaptor protein that interfaces with many pathways activated in lung cancer. It has been assumed that IRS-1 promotes tumor growth through its ability to activate PI3K signaling downstream of the insulin-like growth factor receptor. Surprisingly, tumors with reduced IRS-1 staining in a human...

Guiding colloids with a sense of smell [Commentaries]

PNAS Early Edition Articles - Wed, 07/20/2016 - 12:46
The last decades have seen the impressive rise of nanotechnology and nanomedicine, and the concomitant integration of nanometer-sized agents (1) and laboratory-on-a-chip devices (2). The imagination can hardly keep up with the variety of nanoparticles that are currently synthesized by scalable technologies, not to speak of the sheer inexhaustible range...

GOP Platform: It’s Time To Get Rid Of The EPA

Climate Depot - Wed, 07/20/2016 - 11:47
By Michael Bastasch on July 19, 2016 The Republican Party’s 2016 platform proposes getting rid of the Environmental Protection Agency (EPA) as a massive regulatory body and turning it into an “independent bipartisan commission.” “We propose to shift responsibility for environmental regulation from the federal bureaucracy to the states and to transform the EPA into [...]

GROUP CLONES CALIFORNIA GIANT TREES TO COMBAT ‘CLIMATE CHANGE’

Climate Depot - Wed, 07/20/2016 - 11:45
CAMP NELSON, Calif. (AP) — At the foot of a giant sequoia in California’s Sierra Nevada, two arborists stepped into harnesses then inched up ropes more than 20 stories into the dizzying canopy of a tree that survived thousands of years, enduring drought, wildfire and disease. There, the arborists clipped off tips of young branches [...]

Global Warming Expedition Stopped In Its Tracks By Arctic Sea Ice

Climate Depot - Wed, 07/20/2016 - 11:24
Via: http://dailycaller.com/2016/07/20/global-warming-expedition-stopped-in-its-tracks-by-arctic-sea-ice/ By CRAIG BOUDREAU – 10:43 AM 07/20/2016 A group of adventurers, sailors, pilots and climate scientists that recently started a journey around the North Pole in an effort to show the lack of ice, has been blocked from further travels by ice. The Polar Ocean Challenge is taking a two month journey that will see them go [...]

The EPA’s gas mileage testing standards don’t work. At all

Climate Depot - Wed, 07/20/2016 - 11:20
POSTED AT 8:01 AM ON JULY 20, 2016 BY JAZZ SHAW If you’re interested in having a vehicle which is more stingy with gasoline, there’s some good news out this week. There’s also some terrible news. If that leaves you feeling a bit confused, don’t feel too bad because the reports coming out of the [...]

UN pleads for climate accord ratification before mass ‘Clexit’

Climate Depot - Wed, 07/20/2016 - 11:17
By Valerie Richardson – The Washington Times – Tuesday, July 19, 2016 The United Nations has issued a plea for nations to fast-track ratification of the Paris Climate Agreement as some countries are backtracking on support for the deal’s sweeping restrictions on greenhouse gas emissions. U.N. Secretary-General Ban Ki-moon urged nations to attend a “special [...]

Warmists invent: ‘Climate change inaction figures’ – Collect them All

Climate Depot - Wed, 07/20/2016 - 10:45
You’ve likely heard about the new collectibles taking the world by storm: They’re cute, cuddly, and exist only in a virtual world that may be better than the real one. We’re talking about Climate Change Inaction Figures. A project of the National Geographic Channel’s Years of Living Dangerously, these anti-heroes are known for their blind rejection of facts, [...]

Steam generator anomalies to extend Fessenheim 2 outage

World Nuclear News - Wed, 07/20/2016 - 09:10
A serviceability certificate for one of the three steam generators installed at unit 2 of the Fessenheim nuclear power plant, currently offline for maintenance, has been suspended by the French nuclear safety regulator. A number of anomalies were discovered last month in the steel of the component's lower shell.

Europe checks French state aid for Areva restructuring

World Nuclear News - Wed, 07/20/2016 - 08:58
The European Commission has launched an investigation to determine whether the French government's contribution of €4.0 billion ($4.4 billion) towards the financing of the restructuring of Areva meets EU rules on state aid.

Fmr NASA Scientist Dispels Myth Global Warming Is ‘Settled’

Climate Depot - Wed, 07/20/2016 - 08:34
http://dailycaller.com/2016/07/20/former-nasa-scientist-dispels-notion-global-warming-is-settled-science/

Empirical Evidence: Climate Change Driven By Non-CO2 Factors, Experts Find

Climate Depot - Wed, 07/20/2016 - 06:18
(click to enlarge — image source) It is indisputable that significant climate change is a never ending condition: Earth’s climate, due to internal and external forces, is inconstant and variable across regions. Chinese researchers determined that non-CO2 forcings are the principal causes of majors swings in a climate’s temperature, be it cooling and warming. They [...]

One More Official Exposes Real Goal Of Climate Scare – ‘A $7 trillion investment opportunity’

Climate Depot - Wed, 07/20/2016 - 06:14
KERRY JACKSON 3:46 PM ET In recent years we’ve documented the true motivations that are driving the global warming scare. Christiana Figueres, the executive secretary of United Nation’s Framework Convention on Climate Change, who aspires to be U.N. secretary general, has admitted that the goal of environmental activists is to destroy capitalism. One-time U.N. Intergovernmental [...]

WaPo: Work will be a thing of the past?! ‘Workers around the world are suffering from excessive heat fueled by climate change’

Climate Depot - Wed, 07/20/2016 - 06:10
Scorching heat is driving down economic productivity around the world An Indian girl splashes her face with water to keep off the heat as her mother works at a nearby road construction project on a hot summer afternoon in New Delhi in 2014. (AP/Saurabh Das) From construction workers in Dubai to farmers in India, workers around [...]

Here They Go Again: #ExxonKnew Activists to Re-Release Old Documents in Desperate Bid for Relevance

Climate Depot - Wed, 07/20/2016 - 06:05
http://energyindepth.org/national/exxonknew-activists-to-re-release-old-documents-in-desperate-bid-for-relevance/ In its crusade to draw parallels between Big Tobacco and Big Oil, the #ExxonKnew campaign is making its most desperate pitch to date this week, following the publication of a devastating op-ed in the Washington Post authored by Dennis Vacco, a former New York attorney general who actually litigated and settled the Big Tobacco cases and pointed out [...]
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