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UK Met Office Confirms 2014 Continues Global Warming ‘Pause’ – ‘It’s not possible to definitively say which of several recent years was the warmest’

Climate Depot - Tue, 01/27/2015 - 09:59
 the uncertainty ranges mean it’s not possible to definitively say which of several recent years was the warmest.” HadCRUT4 - Click on image to enlarge Quoting the temperature to one hundredth of a degree and the error on that measurement to a tenth of a degree is not normal scientific practice. It is against normal scientific practice [...]

Prof. Roger Pielke Jr.: What Does the Peer-Reviewed Literature Say About Trends in East Coast Winter Storms?

Climate Depot - Mon, 01/26/2015 - 19:38
The images above comes from a 2001 paper by Hirsch et al. (here in PDF) titled, An East Coast Winter Storm Climatology. The top curve shows all East Coast winter storms, and the bottom shows the most intense storms. for the period 1948 to 1997. As the figure implies, they concluded in that analysis: the frequency of [...]

Paper calls Morano ‘Among the loudest skeptics’ – Florida’s Sun Sentinel newspaper features Climate Depot: ‘Skeptic disputes warmest year reports’

Climate Depot - Mon, 01/26/2015 - 19:19
Among the loudest skeptics is Marc Morano, publisher of Climate Depot, who proclaims the National Oceanic and Atmospheric Administration is “conning the public” with a recent report that 2014 was the warmest year on record globally. Morano, a former U.S. Senate Environment and Public Works Committee staff member, calls the report “shameless activism shown by our federal scientists” [...]

Bill Nye on MSNBC Hits ‘Unglued’ Viewers Who Object to Blaming Blizzard on Climate Change

Climate Depot - Mon, 01/26/2015 - 16:34


Climate Depot - Mon, 01/26/2015 - 15:33
NYE on MSNBC – Jan. 26, 2015: But is the economic effect of storms like this is huge. You cancel half of the flights out of the world’s — one of the world’s busiest airports, certainly the eastern seaboard is a very busy area economically for airplane travel and so when you start having big [...]

Kazakhstan mulls construction of two nuclear plants

World Nuclear News - Mon, 01/26/2015 - 15:25
Kazakh energy minister Vladimir Shkolnik said today the government is considering construction of two nuclear power plants in the country.

Energoatom signs amendment to Holtec contract

World Nuclear News - Mon, 01/26/2015 - 15:24
Energoatom and Holtec International have signed an amendment to their contract to build a central used fuel storage facility at the Chernobyl nuclear power plant and the supply of used nuclear dry cask storage systems.

FREE1 regulates protein trafficking and autophagy [Plant Biology]

PNAS Early Edition Articles - Mon, 01/26/2015 - 14:02
Protein turnover can be achieved via the lysosome/vacuole and the autophagic degradation pathways. Evidence has accumulated revealing that efficient autophagic degradation requires functional endosomal sorting complex required for transport (ESCRT) machinery. However, the interplay between the ESCRT machinery and the autophagy regulator remains unclear. Here, we show that FYVE domain...

Control of Igh locus V(D)J recombination [Immunology and Inflammation]

PNAS Early Edition Articles - Mon, 01/26/2015 - 14:02
Ig heavy chain (IgH) variable region exons are assembled from V, D, and J gene segments during early B-lymphocyte differentiation. A several megabase region at the “distal” end of the mouse IgH locus (Igh) contains hundreds of VHs, separated by an intergenic region from Igh Ds, JHs, and constant region...

Optically driven motions of microrods in an LC [Physics]

PNAS Early Edition Articles - Mon, 01/26/2015 - 14:02
A small amount of azo-dendrimer molecules dissolved in a liquid crystal enables translational and rotational motions of microrods in a liquid crystal matrix under unpolarized UV light irradiation. This motion is initiated by a light-induced trans-to-cis conformational change of the dendrimer adsorbed at the rod surface and the associated director...

Chemodetection in fluctuating environments [Systems Biology]

PNAS Early Edition Articles - Mon, 01/26/2015 - 14:02
Variability in the chemical composition of the extracellular environment can significantly degrade the ability of cells to detect rare cognate ligands. Using concepts from statistical detection theory, we formalize the generic problem of detection of small concentrations of ligands in a fluctuating background of biochemically similar ligands binding to the...

Optical antenna enhanced spontaneous emission [Engineering]

PNAS Early Edition Articles - Mon, 01/26/2015 - 14:02
Atoms and molecules are too small to act as efficient antennas for their own emission wavelengths. By providing an external optical antenna, the balance can be shifted; spontaneous emission could become faster than stimulated emission, which is handicapped by practically achievable pump intensities. In our experiments, InGaAsP nanorods emitting at...

Olfactory function loss in drosophilid herbivores [Evolution]

PNAS Early Edition Articles - Mon, 01/26/2015 - 14:02
Herbivory is a key innovation in insects, yet has only evolved in one-third of living orders. The evolution of herbivory likely involves major behavioral changes mediated by remodeling of canonical chemosensory modules. Herbivorous flies in the genus Scaptomyza (Drosophilidae) are compelling species in which to study the genomic architecture linked...

Mitophagy confers resistance to Pseudomonas [Immunology and Inflammation]

PNAS Early Edition Articles - Mon, 01/26/2015 - 14:02
In the arms race of bacterial pathogenesis, bacteria produce an array of toxins and virulence factors that disrupt core host processes. Hosts mitigate the ensuing damage by responding with immune countermeasures. The iron-binding siderophore pyoverdin is a key virulence mediator of the human pathogen Pseudomonas aeruginosa, but its pathogenic mechanism...

Trauma and mortality in medieval Denmark [Anthropology]

PNAS Early Edition Articles - Mon, 01/26/2015 - 14:02
To date, no estimates of the long-term effect of cranial vault fractures on the risk of dying have been generated from historical or prehistoric skeletons. Excess mortality provides a perspective on the efficacy of modern treatment, as well as the human cost of cranial injuries largely related to interpersonal violence...

Protein folding and binding evolve as spandrels [Evolution]

PNAS Early Edition Articles - Mon, 01/26/2015 - 14:02
Binding interactions between proteins and other molecules mediate numerous cellular processes, including metabolism, signaling, and gene regulation. These interactions often evolve in response to changes in the protein’s chemical or physical environment (such as the addition of an antibiotic). Several recent studies have shown the importance of folding stability in...
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