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WaPo: ‘A vote for Trump is a vote for climate catastrophe’ – Trump ‘is a bald-faced denier’

Climate Depot - Tue, 09/20/2016 - 10:36
By Eugene Robinson Opinion writer September 19 at 7:17 PM July and August were the hottest months for the planet since record keeping began. Scientists are confident that 2016 will be the hottest year. Rising sea levels have madeflooding commonplace in several major U.S. cities. And meanwhile, one of our leading presidential candidates says climate [...]

‘Kill the Climate Deniers’ is back with a new club dance album

Climate Depot - Tue, 09/20/2016 - 10:36
Via: http://joannenova.com.au/2016/09/kill-the-climate-deniers-is-back-with-a-new-club-dance-album/ Kill the Climate Deniers is back with a new club dance album Remember the government funded play “Kill The Deniers”? They’re back! This time they’ve got a talkie-dance video (is it funded by the ACT government again? I don’t know). They’re launching it today in Canberra (Weds 21st). See it below — at [...]

Funding gaps remain in decommissioning of East European reactors

World Nuclear News - Tue, 09/20/2016 - 10:21
The estimated cost of decommissioning Soviet-designed, first-generation nuclear power reactors in Bulgaria, Lithuania and Slovakia will be at least €5.7 billion ($6.4 billion), according to the European Court of Auditors. However, it warns this could double if the cost of disposing of high-level radioactive waste is included.

Clathrin-dependent AtPEP1 responses [Plant Biology]

PNAS Early Edition Articles - Tue, 09/20/2016 - 09:26
The Arabidopsis thaliana endogenous elicitor peptides (AtPeps) are released into the apoplast after cellular damage caused by pathogens or wounding to induce innate immunity by direct binding to the membrane-localized leucine-rich repeat receptor kinases, PEP RECEPTOR1 (PEPR1) and PEPR2. Although the PEPR-mediated signaling components and responses have been studied extensively,...

Dynamic AtDAO1 and GH3 modulate auxin homeostasis [Plant Biology]

PNAS Early Edition Articles - Tue, 09/20/2016 - 09:26
The hormone auxin is a key regulator of plant growth and development, and great progress has been made understanding auxin transport and signaling. Here, we show that auxin metabolism and homeostasis are also regulated in a complex manner. The principal auxin degradation pathways in Arabidopsis include oxidation by Arabidopsis thaliana...

SRP recruits translational paused XBP1u to the ER [Cell Biology]

PNAS Early Edition Articles - Tue, 09/20/2016 - 09:26
Unconventional mRNA splicing on the endoplasmic reticulum (ER) membrane is the sole conserved mechanism in eukaryotes to transmit information regarding misfolded protein accumulation to the nucleus to activate the stress response. In metazoans, the unspliced form of X-box–binding protein 1 (XBP1u) mRNA is recruited to membranes as a ribosome nascent...

IAA degradation in Arabidopsis [Plant Biology]

PNAS Early Edition Articles - Tue, 09/20/2016 - 09:26
Auxin represents a key signal in plants, regulating almost every aspect of their growth and development. Major breakthroughs have been made dissecting the molecular basis of auxin transport, perception, and response. In contrast, how plants control the metabolism and homeostasis of the major form of auxin in plants, indole-3-acetic acid...

DAO auxin oxidase in Arabidopsis [Plant Biology]

PNAS Early Edition Articles - Tue, 09/20/2016 - 09:26
Tight homeostatic regulation of the phytohormone auxin [indole-3-acetic acid (IAA)] is essential to plant growth. Auxin biosynthetic pathways and the processes that inactivate auxin by conjugation to amino acids and sugars have been thoroughly characterized. However, the enzyme that catalyzes oxidation of IAA to its primary catabolite 2-oxindole-3-acetic acid (oxIAA)...

Role of clathrin in pattern-triggered immunity [Plant Biology]

PNAS Early Edition Articles - Tue, 09/20/2016 - 09:26
Sensing of potential pathogenic bacteria is of critical importance for immunity. In plants, this involves plasma membrane-resident pattern recognition receptors, one of which is the FLAGELLIN SENSING 2 (FLS2) receptor kinase. Ligand-activated FLS2 receptors are internalized into endosomes. However, the extent to which these spatiotemporal dynamics are generally present among...

MAPK activity dynamics during yeast mating [Cell Biology]

PNAS Early Edition Articles - Tue, 09/20/2016 - 09:26
In response to pheromones, yeast cells activate a MAPK pathway to direct processes important for mating, including gene induction, cell-cycle arrest, and polarized cell growth. Although a variety of assays have been able to elucidate signaling activities at multiple steps in the pathway, measurements of MAPK activity during the pheromone...

Taxol binds differentially to {beta}-tubulin isotypes [Medical Sciences]

PNAS Early Edition Articles - Tue, 09/20/2016 - 09:26
There are seven β-tubulin isotypes present in distinct quantities in mammalian cells of different origin. Altered expression of β-tubulin isotypes has been reported in cancer cell lines resistant to microtubule stabilizing agents (MSAs) and in human tumors resistant to Taxol. To study the relative binding affinities of MSAs, tubulin from...

Auxin catabolism unplugged [Commentaries]

PNAS Early Edition Articles - Tue, 09/20/2016 - 09:26
Plants rely on the levels and concentration gradients of the hormone auxin as crucial information cues to trigger and modulate almost every aspect of their life cycle, from establishing embryo polarity to promoting phototropic and gravitropic responses (1). Thus, it is critical for plants to finely control the levels of...

Clathrin in plant defense [Commentaries]

PNAS Early Edition Articles - Tue, 09/20/2016 - 09:26
Plant cells are equipped with a collection of membrane surface molecular “antennas” specifically sensitive to different signals. They are mostly represented by hundreds of receptor-like kinases (RKs): about 600 encoded in the Arabidopsis genome (1), which allow plants to react swiftly to signals related to the progress of their own...

CNNs for energy-efficient neuromorphic computing [Computer Sciences]

PNAS Early Edition Articles - Tue, 09/20/2016 - 09:26
Deep networks are now able to achieve human-level performance on a broad spectrum of recognition tasks. Independently, neuromorphic computing has now demonstrated unprecedented energy-efficiency through a new chip architecture based on spiking neurons, low precision synapses, and a scalable communication network. Here, we demonstrate that neuromorphic computing, despite its novel...

Antitumor neutrophils induced by radiation therapy [Medical Sciences]

PNAS Early Edition Articles - Tue, 09/20/2016 - 09:26
Radiation therapy (RT), a major modality for treating localized tumors, can induce tumor regression outside the radiation field through an abscopal effect that is thought to involve the immune system. Our studies were designed to understand the early immunological effects of RT in the tumor microenvironment using several syngeneic mouse...

Clean-up completed at Bradwell ponds

World Nuclear News - Tue, 09/20/2016 - 09:19
Magnox Ltd has announced the successful decontamination of ponds used to store used nuclear fuel at the former Bradwell nuclear power plant in Essex, England.

Westinghouse balances new and existing fleet needs

World Nuclear News - Tue, 09/20/2016 - 07:14
Two Westinghouse AP1000s are likely to start up within a year, with hot functional tests at the first-of-a-kind reactor at Sanmen in China on course to finish next month, interim president and CEO José Emeterio Gutiérrez told delegates at the World Nuclear Association's Annual Symposium held in London last week. Fuel loading at Sanmen is expected to take place before the end of the year.

Cheers! ‘Climate Hustle’ premiers on DVD as Wash Post inducts Morano into ‘Deniers Club’ – WaPo featured Morano w/ cartoon image as one of ‘worst offenders’ for ‘stalling action’

Climate Depot - Mon, 09/19/2016 - 14:28
Full WaPo ‘Deniers Club article here: https://www.washingtonpost.com/posteverything/wp/2016/09/16/deniers-club-meet-the-people-clouding-the-climate-change-debate/ WaPo: Marc Morano inducted into ‘Deniers Club’: Climate scientists “deserve to be publicly flogged.” – As a reporter for the ExxonMobil-funded Conservative News Service, Morano helped launch the swift-boat campaign attacking John F. Kerry’s military service in Vietnam. He then went to work as communications director for the leading climate change denier [...]

AT-rich DNA-associated protein controls cell fate [Microbiology]

PNAS Early Edition Articles - Mon, 09/19/2016 - 13:06
Faithful cell cycle progression in the dimorphic bacterium Caulobacter crescentus requires spatiotemporal regulation of gene expression and cell pole differentiation. We discovered an essential DNA-associated protein, GapR, that is required for Caulobacter growth and asymmetric division. GapR interacts with adenine and thymine (AT)-rich chromosomal loci, associates with the promoter regions...

ACOX2 deficiency: A bile acid synthesis defect [Medical Sciences]

PNAS Early Edition Articles - Mon, 09/19/2016 - 13:06
Acyl CoA Oxidase 2 (ACOX2) encodes branched-chain acyl-CoA oxidase, a peroxisomal enzyme believed to be involved in the metabolism of branched-chain fatty acids and bile acid intermediates. Deficiency of this enzyme has not been described previously. We report an 8-y-old male with intermittently elevated transaminase levels, liver fibrosis, mild ataxia,...
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