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Colorado Gazette editorial: CU professor Pielke Jr. derided for climate research

Climate Depot - Tue, 12/06/2016 - 09:50
CU has done a stand-up job supporting Pielke and other faculty who challenge conventional wisdom, censorship and establishment group think. We wish Pielke all the best, but urge him never bury his climate change findings.

Climate scientist faced backlash from the left & WH after his research questioned extreme weather claims

Climate Depot - Tue, 12/06/2016 - 09:44
Roger Pielke Jr claimed he was victim of a witch hunt in an op-ed Friday University Of Colorado professor believes that climate change is real But questions whether hurricanes and droughts are more frequent Says his positions cost him a writing job at Nate Silver’s website 538 Critique debunking his claims remains published on White [...]

Trump Gore meeting – Cause for Concern? 

Climate Depot - Tue, 12/06/2016 - 07:15
Al Gore meets with Ivanka Trump and her father http://www.americanthinker.com/blog/2016/12/al_gore_meets_with_ivanka_trump_and_her_father.html By Thomas Lifson Trump’s approach to his presidency seems to include talking to former and current opponents. Far from inhabiting a bubble, he makes sure to hear the views of others. And Gore has plenty of connections to the world of high tech (he is [...]

Trump could face the ‘biggest trial of the century’ — over climate change

Climate Depot - Mon, 12/05/2016 - 20:40
A few weeks ago, a federal judge in Oregon made headlines when she ruled that a groundbreaking climate lawsuit will proceed to trial. And some experts say its outcome could rewrite the future of climate policy in the United States. The case, brought by 21 youths aged 9 to 20, claims that the federal government [...]

Al Gore: ‘I Felt Good’ About Trump Meeting, Ivanka Is ‘Very Committed’ on Climate Policy

Climate Depot - Mon, 12/05/2016 - 20:31
Former Vice President Al Gore appeared on MSNBC tonight to further discuss his meeting with President-elect Donald Trump and Ivanka Trump. Hayes asked him, “Did you come away encouraged, terrified, or somewhere in between?” Gore said it was “very interesting” and productive.” And while he would not divulge specific details, he made it clear he [...]

EPA Chief warns utilities: ‘Next Administration will never allow’ continuation of Trump policies

Climate Depot - Mon, 12/05/2016 - 16:49
  Published on Dec 5, 2016 Speaking with CNN’s John Sutter, Obama EPA Administrator Gina McCarthy warns America’s utility industry not to invest in coal-fired power plants because the next Administration after Donald Trump’s will shut them down: “They are not going to go backwards… You’ll be asking them to invest in facilities that they [...]

Donald Trump, Ivanka Trump Meet With Al Gore

Climate Depot - Mon, 12/05/2016 - 14:24
Donald Trump and his daughter, Ivanka Trump, met with Al Gore, the former vice president and 2000 Democratic presidential nominee, on Monday in New York City. “I had a lengthy and very productive session with the President-elect,” Gore said after the meeting. “It was a sincere search for areas of common ground. I had a [...]

Emergent structures and dynamics of cell colonies by contact inhibition of locomotion [Biophysics and Computational Biology]

PNAS Early Edition Articles - Mon, 12/05/2016 - 13:59
Cells in tissues can organize into a broad spectrum of structures according to their function. Drastic changes of organization, such as epithelial–mesenchymal transitions or the formation of spheroidal aggregates, are often associated either to tissue morphogenesis or to cancer progression. Here, we study the organization of cell colonies by means...

POWERDRESS and HDA9 interact and promote histone H3 deacetylation at specific genomic sites in Arabidopsis [Plant Biology]

PNAS Early Edition Articles - Mon, 12/05/2016 - 13:59
Histone acetylation is a major epigenetic control mechanism that is tightly linked to the promotion of gene expression. Histone acetylation levels are balanced through the opposing activities of histone acetyltransferases (HATs) and histone deacetylases (HDACs). Arabidopsis HDAC genes (AtHDACs) compose a large gene family, and distinct phenotypes among AtHDAC mutants...

Receptor kinase complex transmits RALF peptide signal to inhibit root growth in Arabidopsis [Plant Biology]

PNAS Early Edition Articles - Mon, 12/05/2016 - 13:59
A number of hormones work together to control plant cell growth. Rapid Alkalinization Factor 1 (RALF1), a plant-derived small regulatory peptide, inhibits cell elongation through suppression of rhizosphere acidification in plants. Although a receptor-like kinase, FERONIA (FER), has been shown to act as a receptor for RALF1, the signaling mechanism...

miR-17~92 family clusters control iNKT cell ontogenesis via modulation of TGF-{beta} signaling [Immunology and Inflammation]

PNAS Early Edition Articles - Mon, 12/05/2016 - 13:59
Invariant natural killer T cells (iNKT) cells are T lymphocytes displaying innate effector functions, acquired through a distinct thymic developmental program regulated by microRNAs (miRNAs). Deleting miRNAs by Dicer ablation (Dicer KO) in thymocytes selectively impairs iNKT cell survival and functional differentiation. To unravel this miRNA-dependent program, we systemically identified...

Concentrator photovoltaic module architectures with capabilities for capture and conversion of full global solar radiation [Engineering]

PNAS Early Edition Articles - Mon, 12/05/2016 - 13:59
Emerging classes of concentrator photovoltaic (CPV) modules reach efficiencies that are far greater than those of even the highest performance flat-plate PV technologies, with architectures that have the potential to provide the lowest cost of energy in locations with high direct normal irradiance (DNI). A disadvantage is their inability to...

UV-B photoreceptor-mediated protection of the photosynthetic machinery in Chlamydomonas reinhardtii [Plant Biology]

PNAS Early Edition Articles - Mon, 12/05/2016 - 13:59
Life on earth is dependent on the photosynthetic conversion of light energy into chemical energy. However, absorption of excess sunlight can damage the photosynthetic machinery and limit photosynthetic activity, thereby affecting growth and productivity. Photosynthetic light harvesting can be down-regulated by nonphotochemical quenching (NPQ). A major component of NPQ is...

Reprogramming cell fate with a genome-scale library of artificial transcription factors [Cell Biology]

PNAS Early Edition Articles - Mon, 12/05/2016 - 13:59
Artificial transcription factors (ATFs) are precision-tailored molecules designed to bind DNA and regulate transcription in a preprogrammed manner. Libraries of ATFs enable the high-throughput screening of gene networks that trigger cell fate decisions or phenotypic changes. We developed a genome-scale library of ATFs that display an engineered interaction domain (ID)...

Casitas B-cell lymphoma (Cbl) proteins protect mammary epithelial cells from proteotoxicity of active c-Src accumulation [Cell Biology]

PNAS Early Edition Articles - Mon, 12/05/2016 - 13:59
Casitas B-cell lymphoma (Cbl) family ubiquitin ligases negatively regulate tyrosine kinase-dependent signal transduction by promoting degradation of active kinases. We and others previously reported that loss of Cbl functions caused hyperproliferation in lymphoid and hematopoietic systems. Unexpectedly, Cbl deletion in Cbl-b–null, Cbl-c–null primary mouse mammary epithelial cells (MECs) (Cbl triple-deficiency)...

The plant component of an Acheulian diet at Gesher Benot Ya'aqov, Israel [Anthropology]

PNAS Early Edition Articles - Mon, 12/05/2016 - 13:59
Diet is central for understanding hominin evolution, adaptation, and environmental exploitation, but Paleolithic plant remains are scarce. A unique macrobotanical assemblage of 55 food plant taxa from the Acheulian site of Gesher Benot Ya‘aqov, Israel includes seeds, fruits, nuts, vegetables, and plants producing underground storage organs. The food plant remains...

Chromosome instability drives phenotypic switching to metastasis [Medical Sciences]

PNAS Early Edition Articles - Mon, 12/05/2016 - 13:59
Chromosome instability (CIN) is the most striking feature of human cancers. However, how CIN drives tumor progression to metastasis remains elusive. Here we studied the role of chromosome content changes in generating the phenotypic dynamics that are required for metastasis. We isolated epithelial and mesenchymal clones from human carcinoma cell...
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